Mostrando entradas con la etiqueta SALUD. Mostrar todas las entradas
Mostrando entradas con la etiqueta SALUD. Mostrar todas las entradas

jueves, 11 de septiembre de 2014

Cannabis use in adolescence has negative impact on education

A study looks to add more fuel to the heated debate around the use of marijuana, as researchers have linked the frequent use of cannabis among adolescents with reduced educational attainment. The study also links frequent use of the drug with other negative health outcomes, such as suicide attempts.

The study's lead author, Dr. Edmund Silins, says that the results "provide strong evidence that the prevention or delay of cannabis use is likely to have broad health and social benefits."
The team, comprised of researchers from Australia and New Zealand, received funding from the Australian Government National Health and Medical Research Council, and the study has been published in The Lancet Psychiatry.

Many researchers are pushing for cannabis to be used in a therapeutic capacity, as a form of pain relief or to alleviate symptoms of conditions such as multiple sclerosis (MS) and post-traumatic stress disorder(PTSD).
However, study author Richard Mattick believes that moves toward the decriminalization and legalization of cannabis also contribute toward "raising the possibility that the drug might become more accessible to young people."
Outside of legal avenues, cannabis is the most widely used illicit drug worldwide. The National Institute on Drug Abuse (NIDA) report that around 7% of US high-school seniors are daily or near-daily cannabis users, with around 46% having tried the drug at some point during their lifetime.
Although the study uses data from adolescents in Australia and New Zealand, the authors state that the rates of cannabis use are similar across high-income countries. For example, they cite that the rates of cannabis use among adults in Australia and New Zealand are 10% and 15% respectively, compared with a rate of 15% in the US.

Does early cannabis use compromise education?

For the study, the researchers utilized the data of 3,765 participants from three large, long-term longitudinal studies, tracking cannabis use alongside several developmental outcomes from before the age of 17 up to the age of 30.
They recorded the frequency of cannabis use as never, less than monthly, monthly or more, weekly or more, or daily. The researchers chose to record the following developmental outcomes:
  • Cannabis dependence
  • Completing high school
  • Depression
  • Obtaining a university degree
  • Suicide attempts
  • Use of other illicit drugs
  • Welfare dependence.
The researchers found significant associations between the frequency of adolescent cannabis use and all of the designated developmental outcomes. After adjusting for potential confounding factors such as socioeconomic status and mental illness, they found that five of the associations remained significant.
Individuals who had used cannabis daily before the age of 17 were 60% less likely to complete high school or obtain a degree than those who had never used cannabis. They were also 18 times more likely to become dependent on cannabis, eight times more likely to use other illicit drugs and seven times more likely to attempt suicide by the age of 25.
Most significantly, the researchers found that the risk of negative developmental outcomes increased relative to the frequency of the cannabis dose. Daily cannabis users experienced the strongest effects of the association.

Impact on reforming legislation


In a linked commentary, Prof. Merete Nordentoft, of the University of Copenhagen, Denmark, explains why these results may have occurred:
"Persistent cannabis use has adverse effects, such as low energy and initiative, and impairment of cognitive functions, and these factors are likely to mediate the harmful effect of cannabis on educational attainment."
The authors say that these findings are consistent with the results of previous studies investigating early cannabis use alongside these developmental outcomes. They suggest that preventing or delaying cannabis use in adolescents could have far-reaching benefits, both socially and with regard to health.
One measure that the authors suggest could be implemented is screening for cannabis use in adolescents as standard practice during visits to doctors, child psychiatrists, school nurses and other health care practitioners. This is due to an estimated lack of self-reporting among adolescent cannabis users.
"Efforts to reform cannabis legislation should be carefully assessed to ensure they reduce adolescent cannabis use and prevent potentially adverse effects on adolescent development," says Dr. Silins.
In spite of this, the authors also acknowledge that within US states where cannabis has been made increasingly available for medical use, there has been no reported increase in use among young people.
The study still urges caution. The landscape is undeniably changing with regard to how cannabis is perceived and utilized, and the authors believe that as this framework changes, the needs of the youth must always be considered in order to prevent adverse developmental outcomes.
Tomado de: Medical News Today. Written by James McIntosh

jueves, 23 de enero de 2014

Intensive lifestyle interventions benefit patients with type 2 diabetes

Lifestyle interventions can have a number of positive effects in the management of type 2 diabetes.
It has been well documented in two landmark clinical trials on the prevention of diabetes that dietary changes and regular physical activity will prevent or delay the development of diabetes in high-risk individuals.

Landmark clinical trials

The Diabetes Prevention Project (DPP), a randomized controlled trial in patients with prediabetes, showed that 7% weight loss, achieved by a lifestyle modification program, reduced the 4-year cumulative incidence of diabetes by 58% vs. a placebo group that made no formal lifestyle changes. The program incorporated individual and group counseling sessions that encouraged a low-fat diet and at least 150 minutes of exercise (brisk walking) per week.
The Finnish Diabetes Prevention Study extended the DPP by looking at the reduction in the incidence of diabetes in high-risk, middle-aged (mean age, 55 years) adults at as much as 5 years post-intervention. The intervention included personal counseling sessions aimed at moderate (5%) weight loss achieved by a low-fat, high-fiber diet and moderate exercise for about 30 minutes per day. The average weight loss at 5 years was only 4.6 lb, but resulted in a lower incidence of diabetes in this population (23%) vs. placebo (11%).
Modest reductions in weight using a combination of dietary modifications and exercise resulted in significant reductions in the incidence of diabetes in high-risk individuals.

Look AHEAD

A more recent analysis of the Action for Health in Diabetes (Look AHEAD) study by Gregg and colleagues examined the association of a long-term intensive weight-loss intervention with the frequency of remission of type 2 diabetes. This was a randomized controlled trial involving more than 4,500 participants followed for 4 years. All participants had type 2 diabetes and a BMI of at least 25 at the beginning of the study. They were randomly assigned to intensive lifestyle intervention or a standard lifestyle intervention.
The intensive intervention involved weekly counseling for the first 6 months, then three sessions per month for 6 months, followed by two sessions per month for remainder of study. The primary aim of the intensive group was a reduction in total caloric intake to 1,200 kcal/day to 1,800 kcal/day, along with 175 minutes/week of exercise.
The standard group received three counseling sessions per year focusing on diet, exercise and social support. The results showed that the intensive intervention group lost significantly more weight and had greater fitness increases. The intensive group also was more likely to achieve remission of their diabetes vs. the control group (7.3% vs. 2%, respectively). It should be noted that more patients achieved partial remission than complete remission. This lends some support to more intensive lifestyle interventions than what is commonly done for many patients with type 2 diabetes. 
Tomado de: Endocrine Today, December 2013 .    James R. Taylor, PharmD, CDE